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Image Search Results
Journal: Hepatology (Baltimore, Md.)
Article Title: The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice
doi: 10.1002/hep.30113
Figure Lengend Snippet: Change in plasma cytokines and hepatic gene expression during progression of NASH. Male C57BL/6J mice carrying human APOE*3‐Leiden and CETP transgenes were fed a “Western” diet for 0‐16 weeks. Control mice were fed for 16 weeks on chow. Plasma levels (picograms per milliliter) of TNF‐α (A), IL‐6 (B), and MCP‐1 (C) were measured by ELISA. Data are mean ± SEM from three mice per group. Liver expression of F4/80 (D), MCP‐1 (E), and Col1a1 (F) was measured by quantitative PCR and normalized to ribosomal protein L4. Fold change was compared to the 0 week diet group. Data are presented as mean ± SEM from 4‐10 mice per group.
Article Snippet: Quantification of plasma cytokines was carried out in a custom multiplexed cytokine enzyme‐linked
Techniques: Clinical Proteomics, Gene Expression, Western Blot, Control, Enzyme-linked Immunosorbent Assay, Expressing, Real-time Polymerase Chain Reaction